Genetic analysis of pseudoexfoliation glaucoma risk in an Irish population
نویسندگان
چکیده
منابع مشابه
Exploring functional candidate genes for genetic association in german patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma.
PURPOSE Pseudoexfoliation (PEX) syndrome is a generalized elastic microfibrillopathy characterized by fibrillar deposits in intra- and extraocular tissues. Genetic and nongenetic factors are known to be involved in its etiopathogenesis. This study was focused on six functional candidate genes involved in PEX material deposition and the analysis of their potential association with PEX syndrome a...
متن کاملPrevalence of Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma in Upper Egypt
BACKGROUND Pseudoexfoliation (PXF) is a recognized risk factor for developing cataract, glaucoma and lens dislocation. PXF is also associated with increased risk of complications during cataract surgery due to poor mydriasis and zonular weakness. The aim of this study is to report the prevalence of pseudoexfoliation among Upper Egyptians attending the ophthalmology clinic of Assiut University H...
متن کاملAnalysis of LOXL1 polymorphisms in a United States population with pseudoexfoliation glaucoma
PURPOSE To identify if recently described LOXL1 (lysyl oxidase-like 1) polymorphisms are associated with pseudoexfoliation glaucoma (XFG) in a United States (U.S.) Caucasian patient population. METHODS Individuals with XFG were identified using standard clinical examination techniques. TaqMan allelic discrimination assays were used to genotype 13 single nucleotide polymorphisms (SNPs) that ta...
متن کاملAnalysis of LOXL1 polymorphisms in a Saudi Arabian population with pseudoexfoliation glaucoma
PURPOSE To investigate whether single nucleotide polymorphisms (SNPs) in the lysyl oxidase-like 1 (LOXL1) gene are associated with pseudoexfoliation glaucoma (PEG) in the Saudi Arabian population. METHODS The coding regions of LOXL1 were fully sequenced in 93 clinically diagnosed PEG patients and 101 healthy controls. Both groups were Saudi Arabs. Previously reported and newly identified SNPs...
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Introduction: Many countries endemic for the rabies virus are popular tourist destinations for travelers from developed countries. This study was designed to assess the level of awareness of rabies in a sample of travelers attending a travel medicine clinic and to assess whether the rabies-specific information provided verbally should be reinforced into a written form before th...
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ژورنال
عنوان ژورنال: Acta Ophthalmologica
سال: 2019
ISSN: 1755-375X,1755-3768
DOI: 10.1111/j.1755-3768.2019.5165